Human Chorionic Gonadotropin and Early Embryogenesis: Review
| Autor: | Sophie Perrier d’Hauterive, Romann Close, Virginie Gridelet, Marie Mawet, Michelle Nisolle, Vincent Geenen |
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| Rok vydání: | 2021 |
| Předmět: |
endocrine system
QH301-705.5 hCG Embryonic Development Chorionic Gonadotropin Catalysis Inorganic Chemistry immunology Animals Humans Protein Isoforms implantation Embryo Implantation Physical and Theoretical Chemistry Biology (General) Molecular Biology QD1-999 Spectroscopy reproductive and urinary physiology urogenital system thyroid function Organic Chemistry General Medicine Computer Science Applications Chemistry Blastocyst embryonic structures pregnancy hormones hormone substitutes and hormone antagonists miscarriages |
| Zdroj: | International Journal of Molecular Sciences, Vol 23, Iss 1380, p 1380 (2022) |
| ISSN: | 1422-0067 |
| Popis: | Human chorionic gonadotropin (hCG) has four major isoforms: classical hCG, hyperglycosylated hCG, free β subunit, and sulphated hCG. Classical hCG is the first molecule synthesized by the embryo. Its RNA is transcribed as early as the eight-cell stage and the blastocyst produces the protein before its implantation. This review synthetizes everything currently known on this multi-effect hormone: hCG levels, angiogenetic activity, immunological actions, and effects on miscarriages and thyroid function. |
| Databáze: | OpenAIRE |
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