Microarray data and pathway analyses of peripheral blood mononuclear cells from healthy subjects after a three weeks grape-rich diet
| Autor: | Rosa Anna Milella a, Marica Gasparro a, Fiammetta Alagna a, 1, Maria Francesca Cardone a, Silvia Rotunno a, 2, Concetta Tiziana Ammollo b, Fabrizio Semeraro b, Apollonia Tullo c, Flaviana Marzano c, Domenico Catalano d, Donato Antonacci a, Mario Colucci b, Domenica D'Elia d |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Pathway analyses Grape intake Health benefits Biology lcsh:Computer applications to medicine. Medical informatics Peripheral blood mononuclear cell Nutrigenetics 03 medical and health sciences 0302 clinical medicine Biochemistry Genetics and Molecular Biology Internal medicine Gene expression medicine lcsh:Science (General) Gene Microarray data 030304 developmental biology 2. Zero hunger 0303 health sciences Multidisciplinary Biological processes Microarray analysis techniques fungi Human health food and beverages Diets 3. Good health Endocrinology Nutrigenomics Mitochondrial biogenesis Peripheral blood mononuclear cells Protein repair lcsh:R858-859.7 030217 neurology & neurosurgery lcsh:Q1-390 |
| Zdroj: | Data in Brief, Vol 29, Iss, Pp-(2020) Data in brief 29 (2020): 105278–105278. doi:10.1016/j.dib.2020.105278 info:cnr-pdr/source/autori:Rosa Anna Milella a, **, Marica Gasparro a, Fiammetta Alagna a, 1, Maria Francesca Cardone a, Silvia Rotunno a, 2, Concetta Tiziana Ammollo b, Fabrizio Semeraro b, Apollonia Tullo c, Flaviana Marzano c, Domenico Catalano d, Donato Antonacci a, Mario Colucci b, Domenica D'Elia d, */titolo:Microarray data and pathway analyses of peripheral blood mononuclear cells from healthy subjects after a three weeks grape-rich diet/doi:10.1016%2Fj.dib.2020.105278/rivista:Data in brief/anno:2020/pagina_da:105278/pagina_a:105278/intervallo_pagine:105278–105278/volume:29 Data in Brief |
| ISSN: | 2352-3409 |
| Popis: | Using Human Gene Expression Microarrays (Agilent) technologies, we investigated changes of the level of gene expression in peripheral blood mononuclear cells of healthy subjects after 21 days of fresh table grape-rich diet and after an additional 28-day washout. Several hundreds of genes were differentially expressed after grape intake or after washout. The functional analysis of these genes detected significant changes in key processes such as inflammation and immunity, thrombosis, DNA and protein repair, autophagy and mitochondrial biogenesis. Moreover, fresh grape intake was found to influence the expression of many long non-coding RNA genes. The data can be valuable for researchers interested in nutrigenetics and nutrigenomics studies and are related to the research article “Gene expression signature induced by grape intake in healthy subjects reveals wide-spread beneficial effects on PBMCs” [1]. Keywords: Peripheral blood mononuclear cells, Microarray data, Pathway analyses, Biological processes, Grape intake, Diets, Human health, Health benefits |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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