Chronic Gingivostomatitis with Esophagitis in Cats
Autor: | T.S. Rallis, Dimitra Psalla, A. Kolokotronis, M. I. Kouki, S. A. Papadimitriou |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Male medicine.medical_specialty 040301 veterinary sciences Oral mucosa inflammation Biopsy Disease Standard Article Chronic gingivostomatitis Cat Diseases Gastroenterology 0403 veterinary science 03 medical and health sciences Internal medicine medicine Esophagitis Animals Prospective Studies Prospective cohort study Saliva Stomatitis CATS General Veterinary business.industry Cat 04 agricultural and veterinary sciences Hydrogen-Ion Concentration medicine.disease Gingivitis Pathophysiology Standard Articles 030104 developmental biology Gastrointestinal disease Case-Control Studies Cats Female Oral disease SMALL ANIMAL business Esophageal metaplasia |
Zdroj: | Journal of Veterinary Internal Medicine |
ISSN: | 1939-1676 0891-6640 |
Popis: | Background Chronic gingivostomatitis in cats (FCG) is a debilitating disease with potentially deleterious effects on overall health. Hypothesis/Objectives Little is known about the pathophysiology and overall impact of FCG. The aims of our study were to investigate whether gingivostomatitis occurs concurrently with esophagitis, if FCG treatment contributes to esophagitis and if esophagitis exacerbates signs of FCG. Animals Fifty-eight cats with clinical signs of FCG and 12 healthy control cats exhibiting no signs of oral disease, all client-owned. Methods Prospective study. Physical, oral and endoscopic examinations were performed on all cats. Measurements of salivary and esophageal lumen pH were obtained from both groups. Biopsies were acquired from sites of esophageal inflammation in cats with FCG and from normal-appearing esophageal mucosa in control cats. Results The majority of cats with clinical signs of FCG exhibited some degree of esophagitis especially in the proximal (44/58) and distal (53/58) parts (P < 0.001) with or without columnar metaplasia, compared to controls. All cats lacked signs related to gastrointestinal disease. Salivary and esophageal lumen pH were not statistically different compared to controls. Conclusions and Clinical Importance Feline chronic gingivostomatitis seems to occur concurrently with esophagitis. Esophagitis also should be managed in cats with chronic gingivostomatitis because it may aggravate the existing condition. |
Databáze: | OpenAIRE |
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