Immunohistochemistry biomarker TP53 expression predicts the survival of thymomas
| Autor: | Hui Qiu, Dongliang Bian, Liting Zhao, Zhenghong Zhu, Fanzhen Lv, Xuelin Zhang, Huibiao Zhang |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Oncology medicine.medical_specialty Multivariate analysis business.industry medicine.medical_treatment Hazard ratio medicine.disease Thymectomy 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Diabetes mellitus Internal medicine Medicine Biomarker (medicine) Immunohistochemistry Original Article Surgery Stage (cooking) business Pathological |
| Zdroj: | Gland Surg |
| ISSN: | 2227-8575 2227-684X |
| Popis: | BACKGROUND: Thymomas are rare malignancies. Thymectomy is the optimal therapy which could prolong the survival of patients. However, prognostic factors of thymomas are not clear. METHODS: Thymomas patients were enrolled from 2001 to 2016. Clinical and pathological prognostic factors of thymomas were evaluated by univariate and multivariate analyses. RESULTS: A total number of 98 patients was eligible for this study. All patients were received complete resection (CR). Diagnostic age [elder than the median 60 vs. younger than 60, hazard ratio (HR) =2.325, P=0.027], Masaoka stage (III vs. I, HR =10.756, P |
| Databáze: | OpenAIRE |
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