Herbal immune-boosters: Substantial warriors of pandemic Covid-19 battle
| Autor: | Puja Ohri, Ajaz Ahmad, Renu Bhardwaj, Sukhmeen Kaur Kohli, Abhay Bhardwaj, Anket Sharma, Kanika Khanna, Parvaiz Ahmad, Ravdeep Kaur, Vinay Bhardwaj |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
ACTH
adrenocorticotrophic hormones Battle viruses Tfh follicular helper T-cells Pharmaceutical Science Review MT metalloprotease APC antigen presenting cell Natural therapeutics 0302 clinical medicine GCSF granulocyte-colony stimulating factor Drug Discovery Pandemic CHM Chinese herbal medicine NF neuro fibromatosis Medicine Chinese Traditional NLRP3 NOD-like receptor proteins PDB protein data bank media_common 0303 health sciences TNF tumor necrosis factor ARC artepillin C Social distance RBD receptor-binding domain R0 basic reproduction number 030220 oncology & carcinogenesis Molecular Medicine MIP1 macrophage inflammatory protein 1 WHO World Health Organisation NK natural killer SARS-CoV severe acute respiratory syndrome 2019-20 coronavirus outbreak medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) media_common.quotation_subject AYUSH ayurvedic yoga and naturopathy unani siddha and homeopathy NLR neutrophil-to-lymphocyte ratio IgG immunoglobulin G ACE2 angiotensin-converting enzyme MVD molegro virtual docker 03 medical and health sciences Globalization Adjuvants Immunologic Political science Immune-System Rebooting Development economics MAPK mitogen activated protein kinases MCP1 monocytechemoattractant protein 1 medicine TCM traditional Chinese medicines Humans PAK-1 Blockers C-1 Caspase-1 MERS-CoV middle east respiratory syndrome Pandemics ARDS acute respiratory distress syndrome 030304 developmental biology Pharmacology ICTV international committee on taxonomy of viruses Plants Medicinal SARS-CoV-2 Public health fungi COVID-19 Traditional medicine IL interleukin Medicine Ayurvedic COVID-19 Drug Treatment Herbal plants IgM immunoglobulin M Complementary and alternative medicine ASCs antibody-secreting cells Immune System Dietary Supplements RNA ribonucleic acid CAPE caffeic acid phenyl ester Plant Preparations SARS-CoV-2 severe acute respiratory syndrome coronavirus-2 Phytotherapy |
| Zdroj: | Phytomedicine |
| ISSN: | 1618-095X |
| Popis: | Highlights • Coronavirus pandemic has created a global alarming situation. • SARS-CoV shares sequence homology with bats, therefore, considered as origin. • Scientists are burning midnight's oil to discover drug or vaccine against this deleterious virus. • Medicinal plants should be explored to find a cure for this disease. • Phyto-constituents are ubiquitously synthesised in plants, effective against SARS-CoV-2. • Clinical trials for herbal formulations are promoted to find drug or vaccine. • Other armours like physical fitness, balanced diet are promoted for boosting immunity. Current scenario depicts that world has been clenched by COVID-19 pandemic. Inevitably, public health and safety measures could be undertaken in order to dwindle the infection threat and mortality. Moreover, to overcome the global menace and drawing out world from moribund stage, there is an exigency for social distancing and quarantines. Since December, 2019, coronavirus, SARS-CoV-2 (COVID-19) have came into existence and up till now world is still in the state of shock.At this point of time, COVID-19 has entered perilous phase, creating havoc among individuals, and this has been directly implied due to enhanced globalisation and ability of the virus to acclimatize at all conditions. The unabated transmission is due to lack of drugs, vaccines and therapeutics against this viral outbreak. But research is still underway to formulate the vaccines or drugs by this means, as scientific communities are continuously working to unravel the pharmacologically active compounds that might offer a new insight for curbing infections and pandemics. Therefore, the topical COVID-19 situation highlights an immediate need for effective therapeutics against SARS-CoV-2. Towards this effort, the present review discusses the vital concepts related to COVID-19, in terms of its origin, transmission, clinical aspects and diagnosis. However, here, we have formulated the novel concept hitherto, ancient means of traditional medicines or herbal plants to beat this pandemic. Graphical abstract Image, graphical abstract |
| Databáze: | OpenAIRE |
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