Reactividad a antígenos del microbioma de vías respiratorias en pacientes con enfermedad alérgica respiratoria
| Autor: | Luis Trejo Gómez-Orozco, Diana Berenice Ochoa-Juárez, Daniel Trejo-Tapia, María Antonieta Suárez-Souto, Lourdes Valadez-Carmona, Martha Marcela Henández-Ortega |
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| Jazyk: | Spanish; Castilian |
| Rok vydání: | 2020 |
| Předmět: |
Staphylococcus aureus
Antígeno bacteriano biology business.industry Medicina Mucous membrane of nose medicine.disease_cause medicine.disease biology.organism_classification Allergic inflammation medicine.anatomical_structure Allergen Staphylococcus epidermidis Allergic response Immunology Candida albicans medicine Immunology and Allergy Bacterial antigen business Dysbiosis Respiratory tract Reacción alérgica |
| Zdroj: | Instituto Politécnico Nacional IPN Redalyc-IPN Revista Alergia México (México) Num.2 Vol.67 |
| Popis: | Background: The prevalence of allergic diseases has increased worldwide. Recent studies have informed that the dysbiosis of some specific members of the human microbiota may enhance the allergic response of the respiratory tract. Objective: To retrospectively explore the role of some microorganisms of the human microbiota on the skin reactivity and their effect on the chronicity of allergic respiratory diseases in humans. Methods: A retrospective analysis of a 5-year database of patients with allergic respiratory tract disease. The frequency and magnitude of the reactivity to 38 different allergens was determined. Results: Dermatophagoides pteronyssinus had the highest frequency of reactivity (93.7 %), followed by the bacterial allergen (a mixture of Staphylococcus aureus and Staphylococcus epidermidis) with a frequency of reactivity of 91.82 %; whereas Candida albicans had a frequency of reactivity of only 79.32 %. The frequency of reactivity to the pollen of native Mexican weeds was even lower ~79 %. Conclusion: The microorganisms of the microbiota that were analyzed in this study seem to have an influence on the development of respiratory allergic inflammation, associated with long-term colonization of the pharynx, nasal mucosa, and sinuses because of these microorganisms. |
| Databáze: | OpenAIRE |
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