Study on the chemical composition, Enzyme inhibition and antioxidant activity of Ziziphora taurica subsp. cleonioides
Autor: | Petros A. Tarantilis, Eleni Kakouri, Rifat Tayyib Sarikurkcu, Cengiz Sarikurkcu |
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Přispěvatelé: | Sarıkürkçü, Cengiz |
Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Ziziphora taurica subsp. cleonioides
antioxidant Antioxidant medicine.medical_treatment Flavonoid Ethyl acetate 01 natural sciences law.invention chemistry.chemical_compound Chlorogenic acid law medicine flavonoid General Materials Science Food science LC–ESI–MS/MS Ziziphora Instrumentation Essential oil Enzyme inhibitory activity Fluid Flow and Transfer Processes chemistry.chemical_classification biology 010405 organic chemistry Process Chemistry and Technology Rosmarinic acid fungi General Engineering food and beverages enzyme inhibitory activity LC-ESI-MS/MS biology.organism_classification 0104 chemical sciences Computer Science Applications 010404 medicinal & biomolecular chemistry chemistry Antibacterial activity |
Zdroj: | Applied Sciences Volume 9 Issue 24 |
Popis: | Ziziphora is a plant used in Turkish and Iran traditional medicine for its antibacterial activity, sedative and stomach soothing properties. Although the chemical profile of the essential oil of different Ziziphora species is well documented, data regarding plant extracts are incomplete. In this study extracts from Ziziphora taurica subsp. cleonioides were obtained using ethyl acetate, methanol and water and the chemical profile of the aerial part of the plant was elucidated. Among the compounds identified, rosmarinic acid was the most abundant (3375.67 ± 38.02 &mu g/mL), at the extract of methanol, followed by chlorogenic acid (3225.10 ± 16.44). Enzyme inhibition activity against &alpha amylase and tyrosinase was also estimated. The ethyl acetate extract showed the highest &alpha amylase activity (1.95 ± 0.04 mg/mL), while the best anti-tyrosinase activity was calculated for the methanolic extract (1.25 ± 0.01 mg/mL). In addition, total phenolic, flavonoid content and antioxidant activity were evaluated. According to our results, bioactivity of the plant is of great interest, nonetheless, at the same time, it is strongly depended on the solvent used during the extraction process. Our data suggest that the plant under study may be an important source to consider against metabolic, skin pigmentation and oxidative stress related disorders. |
Databáze: | OpenAIRE |
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