Transcutaneous spinal direct current stimulation inhibits nociceptive spinal pathway conduction and increases pain tolerance in humans
| Autor: | A. Truini, M. Vergari, A. Biasiotta, S. La Cesa, M. Gabriele, G. Di Stefano, C. Cambieri, G. Cruccu, M. Inghilleri, A. Priori |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male Pain Threshold Laser-Evoked Potentials medicine.medical_treatment Pain tolerance Neural Conduction tsdcs Young Adult Threshold of pain medicine Humans direct current stimulation Neurostimulation neuropathic pain business.industry Cold pressor test Nociceptors spinal cord laser evoked potentials Middle Aged Spinal cord neurostimulation Anesthesiology and Pain Medicine Nociception medicine.anatomical_structure Anesthesia Neuropathic pain Transcutaneous Electric Nerve Stimulation Neuralgia Female business |
| Popis: | Despite concerted efforts from pharmacologic research into neuropathic pain, many patients fail to achieve sufficient pain relief with medication alone. For this reason, increasing interest centres on neurostimulation techniques. We assessed whether transcutaneous spinal direct current stimulation (tsDCS) modulates conduction in ascending nociceptive spinal pathways. We measured changes induced by anodal and cathodal tsDCS over the thoracic spinal cord on face- and foot-laser evoked potentials (LEPs) and foot-cold pressor test responses in 20 healthy subjects. Whereas anodal tsDCS reduced the amplitude of the N1 and N2 components of foot-LEPs (P |
| Databáze: | OpenAIRE |
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