Temperature-modulated adsorption of poly(N-isopropylacrylamide)-grafted ferritin on solid substrate

Autor: Kaoru Tamada, Teruo Okano, Tomohiro Hayashi, Yasuhiro Ikezoe, Masayuki Yamato, Yoshikazu Kumashiro, Masahiko Hara, Youichi Okabayashi
Rok vydání: 2012
Předmět:
Zdroj: Colloids and Surfaces B: Biointerfaces. 95:57-64
ISSN: 0927-7765
Popis: Ferritin grafted with temperature-responsive poly(N-isopropylacrylamide) (PIPAAm-ferritin) was synthesized by a coupling reaction using PIPAAm and ferritin for obtaining stimuli-responsive biomaterials. The hydrodynamic diameter of PIPAAm-ferritins in aqueous solution increased at 37 ◦C at a higher protein concentration (>0.2 mg/mL) because of the intermolecular aggregation through the hydrophobic interaction of PIPAAm chains. On the other hand, PIPAAm-ferritins at a lower concentration (
Databáze: OpenAIRE