Prevalence of Psychiatric Comorbidity in Symptomatic Gastroesophageal Reflux Subgroups
| Autor: | Serhat Bor, Rukiye Vardar, Baybars Veznedaroglu, Esra Yildirim, Mustafa Melih Bilgi |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Physiology Population Comorbidity Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Prevalence Outpatient clinic Humans education Depression (differential diagnoses) education.field_of_study business.industry Somatosensory amplification Mental Disorders Beck Depression Inventory Middle Aged medicine.disease humanities digestive system diseases Cross-Sectional Studies 030220 oncology & carcinogenesis GERD Gastroesophageal Reflux Anxiety 030211 gastroenterology & hepatology Female medicine.symptom business |
| Zdroj: | Digestive diseases and sciences. 62(4) |
| ISSN: | 1573-2568 |
| Popis: | Limited data exist regarding the psychosocial aspects of gastroesophageal reflux disease (GERD). Some GERD subgroups, such as functional heartburn and hypersensitive esophagus, might show different psychiatric comorbidities than others. We aimed to evaluate the psychiatric comorbidities of GERD subgroups using a cross-sectional design. A group of GERD patients at a tertiary outpatient clinic were evaluated via upper GIS (gastrointestinal system) endoscopy, esophageal manometry, and 24-h impedance–pH monitoring. Thirty-nine patients diagnosed with erosive reflux disease, 44 with non-erosive reflux disease, 20 with functional heartburn, 11 with hypersensitive esophagus, and 44 healthy controls participated. Psychiatric diagnoses were made using the Structured Clinical Interview for Diagnostics and Statistical Manual of Mental Disorders IV. Psychometric measurements of the patients were performed using the Somatosensory Amplification Scale, Beck Depression Inventory, State-Trait Anxiety Inventory, and Short-Form 36. Healthy controls were evaluated with the same psychometric scales except for the Short-Form 36. All of the GERD subgroups were significantly more depressed than the control group. Depressive disorders were significantly more prevalent in the functional heartburn group than in the non-erosive reflux disease and erosive reflux disease groups. The trait anxiety level of the functional heartburn group was significantly higher than those of the control and non-erosive reflux disease groups. The quality of life scores of the GERD subgroups were significantly lower than the population standards. Depressive disorders were frequently comorbid in the GERD subgroups studied (30–65 %). It is essential to consider the high prevalence rates of comorbid depression when managing GERD. |
| Databáze: | OpenAIRE |
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