Metabolism and Distribution of [2,3-14C]Acrolein in Laying Hens
| Autor: | Milan A. Berge, Halina E. Caravello, Richard A. Parent, Laurie C. Wilkes, Mark G. Hennes, Laura J. Servatius, Michele L. Loftus, Dale E. Sharp |
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| Rok vydání: | 2001 |
| Předmět: |
Meat
Oviposition Administration Oral Body weight chemistry.chemical_compound Expired air Animal science Glycerol Animals Distribution (pharmacology) Tissue Distribution Carbon Radioisotopes Acrolein Muscle Skeletal Biotransformation Chromatography biology General Chemistry Metabolism Pesticide biology.organism_classification chemistry Female General Agricultural and Biological Sciences Chickens Bacteria |
| Zdroj: | Journal of Agricultural and Food Chemistry. 49:1639-1647 |
| ISSN: | 1520-5118 0021-8561 |
| DOI: | 10.1021/jf000079r |
| Popis: | The metabolism and distribution of [2,3-(14)C]-acrolein were studied in 10 laying hens orally administered 1.09 mg/kg of body weight/day for 5 days. Eggs, excreta, and expired air were collected. The hens were killed 12-14 h after the last dose and edible tissues collected. The nature of radioactive residues was determined in tissues and eggs. All of the identified metabolites were the result of the incorporation of acrolein-derived radioactivity into normal natural products of intermediary metabolism in the hen except for 1,3-propanediol, which is a known degradation product of glycerol in bacteria. |
| Databáze: | OpenAIRE |
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