Whole-body MRI in children: Would a 3D STIR sequence alone be sufficient for investigating common paediatric conditions? A comparative study

Autor: Marc Carpentier, Pierre-Alexandre Alois Poletti, Solène Ferrey, Sylviane Hanquinet, Mehrak Anooshiravani, Laura Merlini
Rok vydání: 2016
Předmět:
Child abuse
Male
Neoplasms/diagnostic imaging
Pediatrics
medicine.medical_specialty
Adolescent
Whole body mri
Whole Body Imaging/methods
ddc:616.0757
Sensitivity and Specificity
Imaging
Magnetic Resonance Imaging/methods
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Imaging
Three-Dimensional
Neoplasms
Three-Dimensional/methods
medicine
Humans
Radiology
Nuclear Medicine and imaging
Whole Body Imaging
Child Abuse
Preschool
Child
030203 arthritis & rheumatology
business.industry
Chronic recurrent multifocal osteomyelitis
Infant
Reproducibility of Results
General Medicine
Gold standard (test)
medicine.disease
Predictive value
Magnetic Resonance Imaging
Pediatrics/methods
Histiocytosis
Suspected child abuse
Bone Diseases/diagnostic imaging
Child
Preschool
Child Abuse/diagnosis
Female
Radiology
Bone Diseases
business
Pediatric population
Zdroj: European Journal of Radiology, Vol. 88 (2017) pp. 155-162
ISSN: 1872-7727
0720-048X
Popis: Objectives To test the performance of a single 3D IR T2-Weighted sequence compared to a Whole-body MRI protocol including DWI, T1-Weighted and STIR 3D IR (3S) in a pediatric population. Methods Two radiologists (15 and 30 years of experience),reviewed WBMRIs: first the STIR alone and 2 weeks later the 3S protocol. The indications were variable. Only positive findings were explicitly reported. A third reader compared the results to gold standard (GS) exams specific for the pathology. Agreement between the two readers, sensitivity and positive predictive value of STIR were calculated. Results fifty-four WBMRIs were included (16 suspected child abuse, 8 chronic recurrent multifocal osteomyelitis (CRMO), 11 lymphomas, 4 osteosarcomas, 9 neuroblastomas, 6 histiocytosis). The mean age was 6 years 10 months, range: 1 month to 15 years. Agreement between readers was of 0.87 [0.82–0.91] for 3D STIR, and 0.89 [0.83–0.93] for the 3S protocol. For reader 1 sensitivity of 3D STIR was 81.6% and of 3S 81.0%. For reader 2 it was 74.1% for 3D STIR and 74.7% for 3S. For both readers and for both protocols, the positive predictive value (PPV) depended on the type of disease (for example 100% histocytosis and osteosarcomas, >90% for child abuse, >85% CRMO but Conclusions Sensitivities were not different between the 2 protocols, for each reader and were different between the 2 readers for each protocol.
Databáze: OpenAIRE
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