Efficacy of dialysis in peritoneal dialysis: utility of bioimpedance to calculate Kt/V and the search for a target Kt

Autor: J. Masiá Mondéjar, A. Ortega Cerrato, C. Gómez Roldán, Juan Pérez-Martínez, F. Llamas Fuentes, A. Pérez Rodríguez, G. Martínez Fernández
Rok vydání: 2012
Předmět:
Zdroj: Clinical and Experimental Nephrology. 17:261-267
ISSN: 1437-7799
1342-1751
DOI: 10.1007/s10157-012-0671-x
Popis: To calculate Kt/V, volume (V) is usually obtained by Watson formula, but bioimpedance spectroscopy (BIS) is a simple and applicable technique to determinate V, along with other hydration and nutrition parameters, in peritoneal dialysis (PD) patients. Dialysis efficacy can also be measured with Kt, but no experience exists in PD, so there is no reference/target value for Kt that must be achieved in these patients to be considered adequately dialyzed. We evaluated the efficacy of PD with Kt/V using Watson formula and BIS for V calculation, assessed hydration status in a PD unit by data obtained by BIS, and attempted to find a reference Kt from the Kt/V previously obtained by BIS. In this observational prospective study of 78 PD patients, we measured V using BIS (V bis) and Watson formula (V w) and calculated weekly Kt/V using both volumes (Kt/V bis/V bis and Kt/V w). With the BIS technique, we obtained and subsequently analyzed other hydration status parameters. We achieved a reference Kt, extrapolating the value desired (weekly Kt/V 1.7) to the target Kt using the simple linear regression statistical technique, basing it on the results of the previously calculated Pearson’s linear correlation coefficient. Volume was 1.8 l higher by Watson formula than with BIS (p
Databáze: OpenAIRE