Household Pet Ownership and the Microbial Diversity of the Human Gut Microbiota
| Autor: | Ashley E. Kates, Omar Jarrett, Joseph H. Skarlupka, Ajay Sethi, Megan Duster, Lauren Watson, Garret Suen, Keith Poulsen, Nasia Safdar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Adult DNA Bacterial Male Microbiology (medical) dogs Adolescent Cross-sectional study Microbial diversity 030106 microbiology Immunology lcsh:QR1-502 Zoology Biology 16s rRNA sequencing Microbiology lcsh:Microbiology 03 medical and health sciences Feces Young Adult Human gut Cellular and Infection Microbiology RNA Ribosomal 16S Animals Humans Microbiome Aged Original Research Aged 80 and over Bacteria cats Illumina miseq High-Throughput Nucleotide Sequencing Pets Middle Aged Gut microbiome Gastrointestinal Microbiome Pet ownership 030104 developmental biology Infectious Diseases Case-Control Studies cross-sectional design Alpha diversity Female epidemiology |
| Zdroj: | Frontiers in Cellular and Infection Microbiology Frontiers in Cellular and Infection Microbiology, Vol 10 (2020) |
| ISSN: | 2235-2988 |
| DOI: | 10.3389/fcimb.2020.00073 |
| Popis: | The human gut microbiome has a great deal of interpersonal variation due to both endogenous and exogenous factors, like household pet exposure. To examine the relationship between having a pet in the home and the composition and diversity of the adult gut microbiome, we conducted a case-control study nested in a larger, statewide study, the Survey of the Health of Wisconsin. Stool samples were collected from 332 participants from unique households and analyzed using 16S rRNA sequencing on the Illumina MiSeq. One hundred and seventy-eight participants had some type of pet in the home with dogs and cats being the most prevalent. We observed no difference in alpha and beta diversity between those with and without pets, though seven OTUs were significantly more abundant in those without pets compared to those with pets, and four were significantly more abundant in those with pets. When stratifying by age, seven of these remained significant. These results suggest that pet ownership is associated with differences in the human gut microbiota. Further research is needed to better characterize the effect of pet ownership on the human gut microbiome. |
| Databáze: | OpenAIRE |
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