Paraneoplastic Hypoglycemia in Hepatocarcinoma: Case Report and Literature Review
| Autor: | Vanessa Lopez-Montoya, Alejandro Román-González, Carlos Andrés Regino, Jose C Alvarez, Fernado López-Urbano |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
endocrine system diseases medicine.medical_treatment Octreotide Context (language use) somatostatin 030204 cardiovascular system & hematology Hypoglycemia Gastroenterology Glucagon 03 medical and health sciences 0302 clinical medicine Internal medicine medicine therapeutic chemoembolization hepatitis b business.industry Insulin Endocrinology/Diabetes/Metabolism General Engineering nutritional and metabolic diseases hepatocellular carcinoma Hepatitis B medicine.disease hypoglycemia Parenteral nutrition Oncology Hepatocellular carcinoma business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| DOI: | 10.7759/cureus.12013 |
| Popis: | Hypoglycemia is a common medical emergency in the context of insulin treatment in diabetic patients and oral hypoglycemic agents such as sulfonylureas. In anecdotal cases, hypoglycemia is associated with non-islet cell tumor-induced hypoglycemia (NICTH). In hepatocellular carcinoma (HCC), it has been reported in 4-27% of patients, and it is associated with poor prognosis. We present a case report of a patient with hypoglycemia associated with HCC secondary to chronic hepatitis B virus infection without response to treatment with glucagon, steroids, octreotide, and embolizations, who required parenteral nutrition at home. Even though hypoglycemia associated with HCC is a recognized entity, there is not sufficient evidence in its treatment and prevention. The article aims to review the literature on prevention and therapeutic options. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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