Data linkage analysis of giant cell arteritis in Italy: Healthcare burden and cost of illness in the Italian region of Friuli Venezia Giulia (2001-2017)

Autor: Milena Bond, Elena Cavallaro, Da Riol Rosalia Maria, Francesca Valent, Luca Quartuccio, Elena Treppo, Christian Dejaco, Annarita Tullio, Salvatore De Vita
Rok vydání: 2019
Předmět:
Male
administrative databases
Time Factors
Databases
Factual

Office Visits
Health Status
costs
0302 clinical medicine
Cost of Illness
Health care
Prevalence
030212 general & internal medicine
Registries
Hospital Costs
Referral and Consultation
Aged
80 and over

education.field_of_study
Health Care Costs
Middle Aged
Hospitalization
Italy
arteritis
Female
Medical Record Linkage
Cardiology and Cardiovascular Medicine
Vasculitis
Immunosuppressive Agents
Population
Giant Cell Arteritis
Specialty
Drug Costs
03 medical and health sciences
Rheumatology
medicine
Internal Medicine
Humans
Arteritis
giant cell
Medical prescription
education
Aged
Retrospective Studies
030203 arthritis & rheumatology
business.industry
Retrospective cohort study
medicine.disease
Giant cell arteritis
prevalence
business
Administrative Claims
Healthcare

Demography
Zdroj: Vascular medicine (London, England). 25(2)
ISSN: 1477-0377
Popis: Giant cell arteritis (GCA) is the most common vasculitis in adults. However, comprehensive analyses of the healthcare burden are still scarce. The aim of the study is to report the healthcare burden and cost of illness of GCA in the Friuli Venezia Giulia (FVG) region of Italy, based on a data linkage analysis. To this end, a retrospective study was conducted through the integration of many administrative health databases of the FVG region as the source of information. Cases were identified from two verified, partially overlapping sources (the rare disease registry and medical exemption database). From 2001 to 2017, 208 patients with GCA were registered. The prevalence of GCA in the population aged ⩾ 45 years as of December 31, 2017 was 27.2/100,000 inhabitants (95% CI 23.5–31.4). The mean time of observation was 4.5 ± 3.6 years. A total of 3182 visits (338 per 100 patient-years) was recorded. The most frequent specialty visits were rheumatology ( n = 610, 19.2%), followed by internal medicine ( n = 564, 17.7%). A total of 287 hospitalizations (30 per 100 patient-years) were reported. A total of 13,043 prescriptions (1386 per 100 patient-years) were registered. More than half of the patients were prescribed an immunosuppressive agent. The overall estimated direct healthcare cost was €2,234,070, corresponding to €2374 per patient-year. Overall, GCA is a rare disease which implies a high healthcare cost.
Databáze: OpenAIRE