Pulmonary Emphysema
| Autor: | Shinichi Taura, Yoshio Kitazume, Toshizumi Shirai, Shinichi Ohdama, Shiro Satoh, Yuji Kimula |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
High-resolution computed tomography medicine.medical_specialty Percentile Lung Neoplasms Pulmonary function testing Diagnosis Differential Correlation Perimeter Predictive Value of Tests Hounsfield scale Image Processing Computer-Assisted medicine Humans X-Ray Intensifying Screens Radiology Nuclear Medicine and imaging Prospective Studies Lung Aged Aged 80 and over medicine.diagnostic_test Minimum intensity projection business.industry Reproducibility of Results Middle Aged respiratory system Respiratory Function Tests respiratory tract diseases medicine.anatomical_structure Pulmonary Emphysema Respiratory Mechanics Radiographic Image Interpretation Computer-Assisted Female Radiology business Tomography Spiral Computed |
| Zdroj: | Journal of Computer Assisted Tomography. 32:576-582 |
| ISSN: | 0363-8715 |
| DOI: | 10.1097/rct.0b013e31814b276a |
| Popis: | Objective: To prospectively evaluate the use of minimum-intensity projection (minIP) imaging, high-resolution (HR) computed tomography (CT), and pulmonary function tests for quantifying emphysema with histopathologic examination. Methods: MinIP and HRCT imaging data (n = 23) were obtained, and relative areas of the lung with attenuation values below thresholds from −940 to −1000 Hounsfield units (HU) and first to 13th percentiles were calculated for both data. Pulmonary function tests were performed before lung resection. These parameters were compared with mean alveolar perimeters measured on resected samples. Results: Strongest correlations with mean alveolar perimeter were obtained at −990 HU and the fifth percentile by minIP, −1000 HU and the seventh percentile by HRCT, and diffusion capacity. The correlation between the mean alveolar perimeter and relative areas below −990 HU by minIP showed significantly higher extension (0%-51%) than those below −1000 HU by HRCT (1%-21%). Conclusions: MinIP imaging is more than 2½ times more predictive for quantifying emphysema than HRCT, although diffusion capacity of lung for carbon monoxide is also a valid index. |
| Databáze: | OpenAIRE |
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