The human milk microbiota is modulated by maternal diet
| Autor: | Julia de Melo Iaucci, Susana Marta Isay Saad, Susanne Brix, Cristiane Hermes Sales, Karsten Kristiansen, Christian Hoffmann, Regina Mara Fisberg, Niels Banhos Danneskiold-Samsøe, Carla R. Taddei, Vanessa Pereira Cabral, Asker Daniel Brejnrod, Marina Padilha, Ramon V. Cortez |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Breast milk breastfeeding Corynebacterium Breastfeeding Gut colonization Gut flora medicine.disease_cause Microbiology digestive system Article 03 medical and health sciences fluids and secretions SDG 3 - Good Health and Well-being Virology Lactation gut colonization medicine microbiota maternal diet Maternal diet Food science lcsh:QH301-705.5 Bifidobacterium Pregnancy 030109 nutrition & dietetics biology Streptococcus Microbiota DIETA biology.organism_classification medicine.disease 030104 developmental biology medicine.anatomical_structure lcsh:Biology (General) breast milk |
| Zdroj: | Padilha, M, Danneskiold-Samsøe, N B, Brejnrod, A, Hoffmann, C, Cabral, V P, Iaucci, J D M, Sales, C H, Fisberg, R M, Cortez, R V, Brix, S, Taddei, C R, Kristiansen, K & Saad, S M I 2019, ' The human milk microbiota is modulated by maternal diet ', Microorganisms, vol. 7, no. 11, 502 . https://doi.org/10.3390/microorganisms7110502 Microorganisms Padilha, M, Danneskiold-Samsøe, N B, Brejnrod, A, Hoffmann, C, Cabral, V P, Iaucci, J D M, Sales, C H, Fisberg, R M, Cortez, R V, Brix, S, Taddei, C R, Kristiansen, K & Saad, S M I 2019, ' The Human Milk Microbiota is Modulated by Maternal Diet ', Microorganisms, vol. 7, no. 11, 502 . https://doi.org/10.3390/microorganisms7110502 Volume 7 Issue 11 Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP Microorganisms, Vol 7, Iss 11, p 502 (2019) |
| Popis: | Human milk microorganisms contribute not only to the healthy development of the immune system in infants, but also in shaping the gut microbiota. We evaluated the effect of the maternal diet during pregnancy and during the first month of lactation on the human milk microbiota in a cross-sectional study including 94 healthy lactating women. Microbiota composition was determined by 16S rDNA profiling and nutrient intake assessed through food questionnaires. Thirteen genera were present in at least 90% of all samples, with three genera present in all samples: Streptococcus, Staphylococcus, and Corynebacterium. Cluster analysis indicated two distinct compositions: one marked by a high abundance of Streptococcus (cluster 1), and other by a high abundance of Staphylococcus (cluster 2). A global association with milk microbiota diversity was observed for vitamin C intake during pregnancy (p = 0.029), which was higher for cluster 2 individuals (cluster 2 median = 232 mg/d cluster 1 = 175 mg/d p = 0.02). Positive correlations were found between Bifidobacterium in the milk and intake of polyunsaturated and linoleic fatty acids during the lactation period (p < 0.01). We show that maternal diet influences the human milk microbiota, especially during pregnancy, which may contribute in shaping the gut microbiota. |
| Databáze: | OpenAIRE |
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