Thrombocytopenia as a Diagnostic Marker for Malaria in Patients with Acute Febrile Illness
| Autor: | Gebru Hailu, Angesom Gebreweld, Daniel Getacher Feleke, Temesgen Fiseha, Yonas Erkihun |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Article Subject RC955-962 030106 microbiology 030231 tropical medicine Microbiology 03 medical and health sciences 0302 clinical medicine Arctic medicine. Tropical medicine Internal medicine parasitic diseases medicine In patient medicine.diagnostic_test business.industry Area under the curve Curve analysis Febrile illness Complete blood count Diagnostic marker General Medicine medicine.disease Hematological abnormality Parasitology business Malaria Research Article |
| Zdroj: | Journal of Tropical Medicine Journal of Tropical Medicine, Vol 2021 (2021) |
| ISSN: | 1687-9694 1687-9686 |
| Popis: | Background. Thrombocytopenia is the most common hematological abnormality in patients with acute malaria. This study aimed to determine the role of thrombocytopenia as a diagnostic marker for malaria in patients with acute febrile illness. Method. A cross-sectional health facility-based study was conducted on 423 consecutively selected acute febrile patients at Ataye District Hospital from February to May 2019 GC. A complete blood count and malaria microscopy were performed for each acute febrile patient. ROC curve analysis was performed to calculate sensitivity, specificity, positive predictive value, and negative predictive value of platelet count in predicting malaria. A P ≤ 0.05 was considered statistically significant. Result. Out of the 423 acute febrile patients, 73 (17.3%) were microscopically confirmed malaria cases and the rest 350 (82.7%) patients had negative blood film results. Of the microscopically confirmed malaria cases, 55 (75.34%) were P. vivax and 18 (24.66%) were P. falciparum. The prevalence of thrombocytopenia among malaria patients (79.5%) was significantly higher than those in malaria negative acute febrile patients (13.7%), P |
| Databáze: | OpenAIRE |
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