Chronic neurobrucellosis due to Brucella melitensis
| Autor: | Peter Gaustad, Aira Bucher, Eivind Pape |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Microbiology (medical)
Adult Male Agglutination Turkey Brucellaceae Deafness Brucellosis Cerebrospinal fluid Trimethoprim Sulfamethoxazole Drug Combination medicine Humans Doxycycline Paraplegia General Immunology and Microbiology biology business.industry General Medicine bacterial infections and mycoses medicine.disease biology.organism_classification Trimethoprim Virology Infectious Diseases Immunology Rifampin business Rifampicin medicine.drug Brucella melitensis |
| Zdroj: | Scandinavian journal of infectious diseases. 22(2) |
| ISSN: | 0036-5548 |
| Popis: | A 20-year-old male Turkish immigrant to Norway suffering from severe chronic neurobrucellosis with spastic paraplegia and deafness is presented. The diagnosis was established by isolation of Brucella melitensis from cerebrospinal fluid (CSF) culture. Brucella antibody agglutination titers were high in serum and CSF. In spite of intensive, prolonged treatment with a combination of trimethoprim-sulfamethoxazole (TPM-SMZ), rifampicin and doxycycline, the course of the illness was characterized by relapses and severe neurological defects. |
| Databáze: | OpenAIRE |
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