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Commelina africana L. is widespread in southern Africa, including DR Congo, where it traditionally used for skin disorders. Although an ethnobotanical survey was carried out before, no relevant phytochemical infor-mation is available. The aim of this study was to perform the phytochemical characterisation of C. africana and to discuss the potential bioactivity of the identified phytochemical constituents. Ultra-performance liq-uid chromatography with electrospray ionization quadrupole time-of-flight mass spectrometry (UPLC-ESI-QTOF-MS) was used for profiling and identification of the main phytochemical constituents from leaf extracts (MeOH 90%, DCM, EtOAc, n-BuOH, n-hexane and residue) of C. africana. Twenty-two constituents, comprising flavonoids, phenolic acids, hydroxycinnamic acid amides and lignanamides were identified. Most of the iden-tified compounds are known to have antioxidant and anti-inflammatory properties, which could at least in part explain the traditional use of C. africana against skin disorders.(c) 2023 SAAB. Published by Elsevier B.V. All rights reserved. |
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