Association study and expression analysis of GPC1 gene copy number variation in Chinese Datong yak (Bos grunniens) breed

Autor: Habtamu Abera Goshu, Wu Xiaoyun, Min Chu, Xue Zhi Ding, Bao Pengjia, Ping Yan
Rok vydání: 2019
Předmět:
Zdroj: Italian Journal of Animal Science, Vol 18, Iss 1, Pp 820-832 (2019)
ISSN: 1828-051X
Popis: Copy number variations (CNVs) can cause radical changes in phenotype variation, gene expression and evolutionary adaptation, through gene dosage effects, disruption of transcript arrangement and regulatory polymorphisms. Therefore, the current study was undertaken to investigate the distribution of glypican1 (GPC1) CNVs in five domestic yak breeds, and their association growth traits and gene expression. The data were analysed using real-time quantitative PCR (qPCR). Loss and normal copy number types had a significant (p
Databáze: OpenAIRE
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