Association study and expression analysis of GPC1 gene copy number variation in Chinese Datong yak (Bos grunniens) breed
Autor: | Habtamu Abera Goshu, Wu Xiaoyun, Min Chu, Xue Zhi Ding, Bao Pengjia, Ping Yan |
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Rok vydání: | 2019 |
Předmět: |
Genetics
040301 veterinary sciences 0402 animal and dairy science food and beverages 04 agricultural and veterinary sciences YAK Biology 040201 dairy & animal science Phenotype Gene dosage mrna transcription Breed 0403 veterinary science Variation (linguistics) Gene expression Expression analysis Animal Science and Zoology lcsh:Animal culture sense organs Copy-number variation copy number types growth traits lcsh:SF1-1100 |
Zdroj: | Italian Journal of Animal Science, Vol 18, Iss 1, Pp 820-832 (2019) |
ISSN: | 1828-051X |
Popis: | Copy number variations (CNVs) can cause radical changes in phenotype variation, gene expression and evolutionary adaptation, through gene dosage effects, disruption of transcript arrangement and regulatory polymorphisms. Therefore, the current study was undertaken to investigate the distribution of glypican1 (GPC1) CNVs in five domestic yak breeds, and their association growth traits and gene expression. The data were analysed using real-time quantitative PCR (qPCR). Loss and normal copy number types had a significant (p |
Databáze: | OpenAIRE |
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