Scintigraphy of the hepatobiliar system in patients with pulmonary tuberculosis
| Autor: | Paulo Câmara Marques Pereira, E. T. Silva, R. S. A. Camargo, B. L. Griva |
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| Přispěvatelé: | Universidade Estadual Paulista (Unesp), UNIP, Univ Paulista |
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Pathology
medicine.medical_specialty hepatobiliar system lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 Toxicology Scintigraphy Gastroenterology Excretion Tobacco users Pulmonary tuberculosis lcsh:RA1190-1270 Internal medicine lcsh:Zoology medicine scintigraphy In patient antituberculosis drugs lcsh:QL1-991 pulmonar tuberculosis lcsh:Toxicology. Poisons medicine.diagnostic_test business.industry Hepatobiliary disease Nutritional status Chronic alcohol Infectious Diseases Animal Science and Zoology Parasitology business |
| Zdroj: | Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 12, Iss 2, Pp 234-244 (2006) Journal of Venomous Animals and Toxins including Tropical Diseases v.12 n.2 2006 The Journal of venomous animals and toxins including tropical diseases Universidade Estadual Paulista (UNESP) instacron:UNESP SciELO Repositório Institucional da UNESP Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 12, Issue: 2, Pages: 234-244, Published: APR 2006 Web of Science |
| ISSN: | 1678-9199 |
| Popis: | Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T18:43:32Z No. of bitstreams: 1 S1678-91992006000200006.pdf: 102043 bytes, checksum: 4e124e456a844e7f147560afde81c50f (MD5) Made available in DSpace on 2013-08-22T18:43:32Z (GMT). No. of bitstreams: 1 S1678-91992006000200006.pdf: 102043 bytes, checksum: 4e124e456a844e7f147560afde81c50f (MD5) Previous issue date: 2006-04-01 Made available in DSpace on 2013-09-30T18:19:25Z (GMT). No. of bitstreams: 2 S1678-91992006000200006.pdf: 102043 bytes, checksum: 4e124e456a844e7f147560afde81c50f (MD5) S1678-91992006000200006.pdf.txt: 24483 bytes, checksum: 22122db39081acc19d6cd9fe5337def3 (MD5) Previous issue date: 2006-04-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T13:34:38Z No. of bitstreams: 2 S1678-91992006000200006.pdf: 102043 bytes, checksum: 4e124e456a844e7f147560afde81c50f (MD5) S1678-91992006000200006.pdf.txt: 24483 bytes, checksum: 22122db39081acc19d6cd9fe5337def3 (MD5) Made available in DSpace on 2014-05-20T13:34:38Z (GMT). No. of bitstreams: 2 S1678-91992006000200006.pdf: 102043 bytes, checksum: 4e124e456a844e7f147560afde81c50f (MD5) S1678-91992006000200006.pdf.txt: 24483 bytes, checksum: 22122db39081acc19d6cd9fe5337def3 (MD5) Previous issue date: 2006-04-01 The objective of this paper was to evaluate the hepatobiliary function of patients with pulmonary tuberculosis under triple treatment, using the technetium-99m-DISIDA (99mTc-DISIDA) hepatobiliary scintigraphy. Ten men and three women with pulmonary tuberculosis were subjected to hepatobiliary scintigraphy at the beginning of triple treatment (M1) and two months after it (M2). Patients were from the urban area, of low socioeconomic level, malnourished, and chronic alcohol and/or tobacco users. Ten normal individuals were evaluated as controls. Radiotracer images were acquired on a computerized gamma camera (Orbiter-Siemens) and T1/2 uptake and excretion values were calculated. Nutritional status and serum hepatic enzyme levels for each patient were evaluated at M1 and M2. None presented clinical or laboratory antecedent of hepatobiliary disease. At M1, there were no hepatic serum or kinetic alterations of the 99mTc-DISIDA. At M2, patients presented better nutritional conditions than at M1; there was increased serum aspartate aminotransferase (AST) and reduced excretion time for 99mTc-DISIDA, which was interpreted as a more adaptive than toxic phenomenon, yet not all alterations were significant and none manifested clinically. Apparently, triple treatment acted on the liver inducing the P450 cytochrome enzymatic system, accelerating radiotracer excretion, which follows the same path as the bilirubins. UNESP Botucatu School of Medicine Nuclear Medicine Unit UNIP UNESP Botucatu School of Medicine Department of Tropical Diseases and Diagnostic Imaging UNESP Botucatu School of Medicine Nuclear Medicine Unit UNESP Botucatu School of Medicine Department of Tropical Diseases and Diagnostic Imaging |
| Databáze: | OpenAIRE |
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