Selective Transformations of β-Keto Esters, Promoted by Dowex Basic Ion-Exchange Resins

Autor:	Celine Simon, Francois Clerc, Jean Rodriguez, Jean-Francois Peyronel
Rok vydání:	2003
Předmět:	Addition reaction Bicyclic molecule Chemistry Organic Chemistry Organic chemistry Sequence (biology) General Medicine Physical and Theoretical Chemistry Ion-exchange resin Adduct
Zdroj:	ChemInform. 34
ISSN:	1522-2667 0931-7597
Popis:	Depending on the nature of the Dowex basic ion-exchange resin, cyclic β-keto esters 1 react with α,β-unsaturated aldehydes 2 to give either the corresponding Michael adducts 3 or the highly functionalized bicyclo[3.3.1]nonanes 4 in a one-pot Michael addition−intramolecular aldolization sequence. Some selective transformations of the highly functionalized systems 3 and 4 to provide amino azabicyclo[3.3.1]nonanones 9, polycyclic aminals 10, and azacyclooctene 12 are also presented. (© Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c207a79d9e6ae24f65778399fc2159 https://doi.org/10.1002/chin.200308041 Zobrazit plný text záznamu Plný text