Oxidative stress as determined by glutathione (GSH) concentrations in venous cord blood in elective cesarean delivery versus uncomplicated vaginal delivery
Autor: | Ariela Burg, Adi Yekuda Weintraub, Iris Raz, Orit Paamoni-Keren, Oshra Saphier, Moshe Mazor, Tali Silberstein |
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Rok vydání: | 2007 |
Předmět: |
Adult
medicine.medical_specialty Umbilical cord Gastroenterology Veins chemistry.chemical_compound Venous Cord Blood Pregnancy Internal medicine Elective Cesarean Delivery Humans Medicine Prospective Studies Cesarean Section business.industry Vaginal delivery Infant Newborn Obstetrics and Gynecology Venous blood Glutathione General Medicine Fetal Blood medicine.disease Oxidative Stress medicine.anatomical_structure chemistry Cord blood Anesthesia Female business |
Zdroj: | Archives of Gynecology and Obstetrics. 276:661-661 |
ISSN: | 1432-0711 0932-0067 |
DOI: | 10.1007/s00404-007-0429-y |
Popis: | To determine whether neonates are subject to oxidative stress by the labor process and the mode of delivery by measuring glutathione (GSH) concentrations in umbilical cord venous blood. Forty-eight women with singleton term pregnancies were prospectively recruited and classified as follows: 26 women had a spontaneous uncomplicated vaginal delivery (VD), and 22 women had an elective cesarean delivery (CD). GSH concentration in umbilical venous blood samples was determined by a spectroscopic method. Umbilical cord venous blood GSH levels were significantly lower in the elective CD group than in the VD group (2.2 and 2.7 mM, respectively, P = 0.0003). There was a significantly negative correlation between cord blood pO2 and GSH levels; however, the negative correlation was significantly higher in the elective CD group (P |
Databáze: | OpenAIRE |
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