Oxidative stress as determined by glutathione (GSH) concentrations in venous cord blood in elective cesarean delivery versus uncomplicated vaginal delivery

Autor: Ariela Burg, Adi Yekuda Weintraub, Iris Raz, Orit Paamoni-Keren, Oshra Saphier, Moshe Mazor, Tali Silberstein
Rok vydání: 2007
Předmět:
Zdroj: Archives of Gynecology and Obstetrics. 276:661-661
ISSN: 1432-0711
0932-0067
DOI: 10.1007/s00404-007-0429-y
Popis: To determine whether neonates are subject to oxidative stress by the labor process and the mode of delivery by measuring glutathione (GSH) concentrations in umbilical cord venous blood. Forty-eight women with singleton term pregnancies were prospectively recruited and classified as follows: 26 women had a spontaneous uncomplicated vaginal delivery (VD), and 22 women had an elective cesarean delivery (CD). GSH concentration in umbilical venous blood samples was determined by a spectroscopic method. Umbilical cord venous blood GSH levels were significantly lower in the elective CD group than in the VD group (2.2 and 2.7 mM, respectively, P = 0.0003). There was a significantly negative correlation between cord blood pO2 and GSH levels; however, the negative correlation was significantly higher in the elective CD group (P
Databáze: OpenAIRE