New, optimized, dual-lumen cannula for veno-venous ECMO
| Autor: | Ludwig K. von Segesser, Enrico Ferrari, Denis Berdajs, Saad Abdel-Sayed, Markus J. Wilhelm, Francesco Maisano, Maximilian Halbe |
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| Přispěvatelé: | University of Zurich, von Segesser, Ludwig K |
| Rok vydání: | 2018 |
| Předmět: |
early mobilization
cannulation 2902 Advanced and Specialized Nursing dual medicine.medical_treatment Lumen (anatomy) 610 Medicine & health caval cannula 030204 cardiovascular system & hematology 11171 Cardiocentro Ticino 2705 Cardiology and Cardiovascular Medicine 3311 Safety Research 03 medical and health sciences 0302 clinical medicine Extracorporeal Membrane Oxygenation Inlet pressure bi Extracorporeal membrane oxygenation 2741 Radiology Nuclear Medicine and Imaging Medicine Animals Cannula Humans Radiology Nuclear Medicine and imaging ECLS lumen cannula Advanced and Specialized Nursing business.industry Hemodynamics General Medicine 10020 Clinic for Cardiac Surgery Pump flow Catheter 030228 respiratory system Anesthesia Early mobilization Cattle ECMO Cardiology and Cardiovascular Medicine business Safety Research Revolutions per minute |
| Zdroj: | Perfusion. 33(1_suppl) |
| ISSN: | 1477-111X |
| Popis: | Objective: The present study was designed to assess in vivo a new, optimized, virtually wall-less, dual-lumen, bi-caval cannula for veno-venous ECMO in comparison to a commercially available cannula. Methods: Veno-venous extracorporeal membrane oxygenation (ECMO) was carried out in a bovine study (n=5, bodyweight 75±5kg). Following systemic heparinization, ECMO was established in a trans-jugular fashion through a calibrated 23F orifice, using a new, optimized, virtually wall-less, dual-lumen, bi-caval 24F cannula (Smartcanula LLC, Lausanne, Switzerland) versus a commercially available 23F bi-caval, dual-lumen control cannula (Avalon Elite®, Maquet, Rastatt, Germany) in a veno-venous ECMO setup. Veno-venous ECMO was initiated at 500 revolutions per minute (RPM) and increased by incremental steps of 500 RPM up to 2500 RPM. Catheter outlet pressure, catheter inlet pressure, oxygen saturation and pump flow were recorded at each stage. Results: Mean flow accounted for 0.37±0.04 L/min for wall-less versus 0.29± 0.07 L/min for control at 500 RPM, 0.97±0.12 versus 0.67±0.06 at 1000 RPM, 1.60±0.14 versus 1.16±0.08 at 1500 RPM, 2.31±0.13 versus 1.52±0.13 for 2000 RPM and 3.02±0.5 versus 2.11±0.18 (pConclusion: Compared to the commercially available control cannula, the new, optimized, virtually wall-less, dual-lumen, bi-caval 24F cannula allows for significantly higher blood flows, requires less suction and results in lower injection pressures in vivo. |
| Databáze: | OpenAIRE |
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