Clinical trials evaluating desensitising agents. Some design and analysis issues

Autor:	Robert G. Newcombe, Joon Seong, Nicola X. West
Rok vydání:	2023
Předmět:	Clinical trials confidence interval Dentine hypersensitivity Relative risk reduction General Dentistry
Zdroj:	Newcombe, R, Seong, J & West, N X 2022, ' Clinical trials evaluating desensitising agents : Some design and analysis issues ', Journal of Dentistry, vol. 128, 104380 . https://doi.org/10.1016/j.jdent.2022.104380
ISSN:	0300-5712
DOI:	10.1016/j.jdent.2022.104380
Popis:	IntroductionThe purpose of this short communication is to draw attention to an efficient design for trials to evaluate desensitising agents, and an appropriate statistical analysis.MethodsTwo recent sensitivity trials conducted by the Bristol Dental School Clinical Trials Group are reviewed.ResultsThe methodology used was effective to establish efficacy of the products evaluated.ConclusionsThis methodology is recommended for wider use.Clinical SignificanceEffective clinical trial methodology enables establishment of efficacy of desensitising products leading to patient benefit.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7bbb0fc7f191175e6b50cfadfede45e https://doi.org/10.1016/j.jdent.2022.104380 Zobrazit plný text záznamu Full Text from ScienceDirect