VASOMOTOR FUNCTION OF THE ENDOTHELIUM IN PATIENTS WITH CHRONIC KIDNEY DISEASE AND HYPERTENSION
| Autor: | V. A. Sukhonos, E. Kurshubadze, M. A. Vlasenko, N. V. Demikhova |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Endothelium Urology Vasodilation lcsh:RC870-923 Pathogenesis medicine.artery Internal medicine Immunology and Allergy Medicine Autoregulation Brachial artery hypertension chronic kidney disease endothelial function vasodilation business.industry Biochemistry (medical) medicine.disease lcsh:Diseases of the genitourinary system. Urology medicine.anatomical_structure Blood pressure Nephrology Cardiology cardiovascular system medicine.symptom business Vasoconstriction Kidney disease |
| Zdroj: | Український Журнал Нефрології та Діалізу, Iss 2(38), Pp 70-81 (2017) |
| ISSN: | 2616-7352 2304-0238 |
| Popis: | Investigation of the functional state of the vascular endothelium contributes to the further study of the mechanisms of development and pharmacological correction, particularly in hypertensive patients with chronic kidney disease. Material and Results. The study involved 172 patients with arterial hypertension (AH) in patients with chronic kidney disease. In the study of vascular-motor response to decompression and test with nitroglycerin in 60% of cases occur reduced vasodilatory and in 12.6% constrictor response. Normal character of vasodilation was 27.4%. Endothelium-independent vasodilation in the brachial artery decompression was reduced by 51.1% compared with the control. The growth of endothelium-independent vasoconstriction in the degree III AH was reduced to a lesser degree than the endothelium dependent - by 6.5% and 19.4% (p |
| Databáze: | OpenAIRE |
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