Gastric Electric Activity Assessed by Electrogastrography and Gastric Emptying Scintigraphy in Adolescents With Eating Disorders
| Autor: | Antonella Diamanti, G. C. Ciofetta, A. Ponticelli, G. Bianco, Massimo Castro, T. Sabbi, S. Marinucci, Manuela Gambarara, F. Montecchi, F. Bracci |
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| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty Anorexia Nervosa Adolescent Anorexia Scintigraphy Gastroenterology Statistics Nonparametric Internal medicine mental disorders Humans Medicine Bulimia Dyspepsia Child Radionuclide Imaging Gastric emptying medicine.diagnostic_test Electromyography business.industry Bulimia nervosa Stomach digestive oral and skin physiology Fasting Postprandial Period medicine.disease Surgery Eating disorders Postprandial Gastric Emptying Anorexia nervosa (differential diagnoses) Technetium Tc 99m Sulfur Colloid Pediatrics Perinatology and Child Health Vomiting Female medicine.symptom business |
| Zdroj: | Journal of Pediatric Gastroenterology and Nutrition. 37:35-41 |
| ISSN: | 0277-2116 |
| Popis: | Background Patients with eating disorders can refer to a variety of gastrointestinal symptoms, sometimes to justify reduced food intake and vomiting. The authors investigated whether adolescent patients with eating disorders and dyspeptic symptoms have altered gastric electric activity and abnormal gastric emptying as assessed respectively by electrogastrography and scintigraphy. Methods Twenty-eight patients (18 with anorexia and 10 with bulimia) and 16 healthy volunteers underwent electrogastrography; 20 of the 28 patients (14 with anorexia and 6 with bulimia) underwent gastric emptying scintigraphy. Electrogastrography with bipolar recording lasted 1 hour, 30 minutes before and after a standard meal. Before gastric emptying scintigraphy, patients fasted overnight; during testing, they ingested a solid meal labeled with technetium-99m sulfur colloid. The ratio of fasting to postprandial electrogastrographic variables was evaluated using the Wilcoxon matched-pair test. The Mann- Whitney test was used to compare absolute values for electrogastrographic data in each group. The Student paired t test was used to compare scintigraphic results expressed as percentage of gastric emptying at 60 minutes and as the gastric emptying time (T(1/2)). Results Patients with bulimia significantly differed from those with anorexia and control subjects regarding the amount of normal gastric electric activity and bradygastria, and from patients with anorexia only regarding tachygastria. These electrogastrographic variables did not differ significantly between patients with anorexia and control subjects. Gastric emptying time (T(1/2)) was significantly longer in patients with bulimia than in those with anorexia. Conclusions Adolescent patients with bulimia who complain of dyspeptic symptoms have documentable abnormalities of gastric electric activity and emptying, whereas their counterparts with anorexia, probably owing to their shorter disease duration, do not. |
| Databáze: | OpenAIRE |
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