Genetic linkage studies in Alzheimer's disease

Autor: A. Heyman, Sparkes Rs, M. L. Marazita, Weinberg T, M. A. Spence
Rok vydání: 1986
Předmět:
Zdroj: Neurology. 36:581-584
ISSN: 1526-632X
0028-3878
Popis: We studied 18 families with Alzheimer's disease in family members, under the assumption that the disease is due to a single gene with an autosomal dominant form of inheritance. There was no evidence of linkage of Alzheimer's disease with any of 27 phenotypic gene markers analyzed, but close linkage for the Rh and MNS blood group loci was excluded.
Databáze: OpenAIRE