Designed membrane protein heterodimers and control of their affinity by binding domain and membrane linker properties
Autor: | Chenyang Lan, Anja Stulz, Nicolas P. F. Barthes, Susan Lauw, Pavel Salavei, Manfred Jung, Heiko Heerklotz, Maximilian H. Ulbrich |
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Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Nanoscale. 13:20692-20702 |
ISSN: | 2040-3372 2040-3364 |
Popis: | A pair of designed transmembrane proteins form a dimer at the cell surface, as seen by single molecule imaging. Changes in the linker length or binding domain modulate the 2-dimensional binding affinity. |
Databáze: | OpenAIRE |
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