Aseptic meningo–radiculo–encephalitis presenting initially with urinary retention
| Autor: | Jun Tsuyuzaki, Shinji Ohara, Teruaki Iwahashi, Ryoichi Hayashi, Miho Sasaki |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Central Nervous System Male Pathology medicine.medical_specialty Encephalomyelitis Myelitis Quadriplegia Central nervous system disease Leukocyte Count Erectile Dysfunction Spinal cord compression medicine Humans Meningitis Aseptic Urinary Bladder Neurogenic Polyradiculopathy Radiculopathy Autoantibodies Urinary retention business.industry Encephalomyelitis Acute Disseminated Brain Cauda equina Middle Aged medicine.disease Spinal cord Magnetic Resonance Imaging Cranial Nerve Diseases Paresis medicine.anatomical_structure Neurology Acute disseminated encephalomyelitis Disease Progression Consciousness Disorders Neurology (clinical) medicine.symptom business Spinal Cord Compression |
| Zdroj: | Journal of Neurology. 253:908-913 |
| ISSN: | 1432-1459 0340-5354 |
| DOI: | 10.1007/s00415-006-0131-1 |
| Popis: | We report three male patients with aseptic meningoencephalo- radiculitis presenting with acute urinary retention. Viral antibody titers for herpes types I and II and the PCR studies were negative. The cerebrospinal fluid revealed elevated myelin basic protein. The serum antibodies against a panel of gangliosides, some of which are known to be associated with acquired demyelinating neuropathies, were all negative. The magnetic resonance imaging (MRI) studies revealed spotty T2 high intensities in the basal ganglia, thalamus and brainstem in two patients. In one patient,meningeal gadolinium enhancement of the conus and cauda equina of the spinal cord was recognized. On urodynamic studies, all patients showed features of atonic bladder with or without detrusor hyperactivity. They were treated conservatively without using steroids or immunoglobulins, and made a remarkable functional recovery with the disappearance of abnormal MRI findings.However, all three were left with erectile dysfunction, and two continued to use self-intermittent catheterization at more than 3-year follow-up. There was no recurrence of symptoms. The underlying causes remain unclear, though they may represent a variant of acute disseminated encephalomyelitis. |
| Databáze: | OpenAIRE |
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