Primary atypical teratoid/rhabdoid tumor of the optic nerve: a rare entity in an exceptional location
| Autor: | Iman Elkhiyat, Amina Kili, Mustapha Maher, Youssef Mahdi, Amal Alouan, Jinane Kharmoum, Moulay Zahid Benchrif, Rajae Daoudi, Hakima Elouarradi, Nadia Cherradi |
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| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty Histology Optic nerve Biopsy Case Report Biology Pathology and Forensic Medicine Diagnosis Differential Fatal Outcome Predictive Value of Tests Rhabdoid Antineoplastic Combined Chemotherapy Protocols Biomarkers Tumor medicine Humans Treatment Failure Rhabdoid Tumor Medulloblastoma Atypical teratoid medicine.diagnostic_test Optic Nerve Neoplasms Infant Newborn Teratoma Magnetic resonance imaging General Medicine medicine.disease Immunohistochemistry Magnetic Resonance Imaging Optic Nerve Neoplasm Atypical teratoid rhabdoid tumor Female Differential diagnosis |
| Zdroj: | Diagnostic Pathology |
| ISSN: | 1746-1596 |
| Popis: | ᅟ Atypical teratoid/rhabdoid tumors are rare and highly malignant central nervous system tumors. They have no specific radiological features and often present several histological components that make a problem in differential diagnosis with medulloblastoma and primitive neuroectodermal tumors. We present the case of a newborn girl complained of a gradual proptosis of the left eye secondary to an expansive lesional process of the optic nerve. The location at the optic nerve, reported only twice in the literature, and an exclusive rhabdoid appearance on biopsy added additional differential diagnosis problems. The proptosis worsened and the infant died few days after two cycles of chemotherapy. Virtual slides The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2037718783145212. |
| Databáze: | OpenAIRE |
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