Plateletpheresis efficiency: a comparison of the spectra LRS and AMICUS separators
| Autor: | B. Barrett, P. Rojas, S. Broughton, W.H. Churchill, C. Burgio, S. Christmas, J. Neal, Richard J. Benjamin |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
Hemodilution business.industry Computers Platelet Count Immunology Plateletpheresis Blood volume Hematology Cell Separation Citric Acid Surgery Leukocyte Count Evaluation Studies as Topic Cell separation medicine Immunology and Allergy Humans Paresthesia Prospective Studies Nuclear medicine business Mathematics Retrospective Studies |
| Zdroj: | Transfusion. 39(8) |
| ISSN: | 0041-1132 |
| Popis: | BACKGROUND: Optimizing the yields of platelet-pheresis by increasing collection efficiencies may provide several benefits: to patients, by increasing the dose in single-donor platelet (SDP) units; to the collection center, by increasing the percentage of components that may be split into double units; and/or to the donor, by reducing the duration of donation. STUDY DESIGN AND METHODS: A prospective, randomized study was undertaken to compare the efficiency of platelet collection in paired donations by 21 donors on two cell separators (Spectra LRS, version [v] 5.1; and AMICUS, v2.37). The order of donation was randomly assigned; donations were performed at least 2 weeks apart. A fixed blood volume (4000 mL) was processed by utilizing standard protocols. Findings were confirmed in a retrospective, matched study that compared the two separators by using fixed collection times (90 min). RESULTS: The AMICUS and Spectra LRS separators consistently produced white cell-reduced ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text