The 2020 BMT CTN Myeloma Intergroup Workshop on Immune Profiling and Minimal Residual Disease Testing in Multiple Myeloma
| Autor: | Sarah A. Holstein, Nizar Bahlis, P. Leif Bergsagel, Manisha Bhutani, Niccolo Bolli, Carrie Brownstein, Pierre Demolis, David Foureau, Francesca Gay, Irene M. Ghobrial, Nicole Gormley, Jens Hillengass, Martin Kaiser, Marcela V. Maus, J. Joseph Melenhorst, Maximilian Merz, Michael O. Dwyer, Bruno Paiva, Marcelo C. Pasquini, Nina Shah, Sandy W. Wong, Saad Z. Usmani, Philip L. McCarthy |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Oncology
medicine.medical_specialty Neoplasm Residual Cellular therapy CAR T-cell Article Immune profiling Cell therapy Rare Diseases Bone Marrow Multiple myeloma Internal medicine medicine Humans Immunology and Allergy Endpoint CAR T-cell Minimal residual disease Cancer Transplantation Hematology business.industry Clinical study design High-Throughput Nucleotide Sequencing Cell Biology medicine.disease Endpoint Chimeric antigen receptor Clinical trial Good Health and Well Being Residual Neoplasm Molecular Medicine Diterpenes business |
| Zdroj: | Transplant Cell Ther Transplantation and cellular therapy, vol 27, iss 10 |
| Popis: | The fifth annual Blood and Marrow Transplant Clinical Trials Network Myeloma Intergroup Workshop on Immune Profiling and Minimal Residual Disease Testing in Multiple Myeloma was conducted as one of the American Society of Hematology Annual Meeting Scientific Workshops on Thursday December 3, 2020. This workshop focused on four main topics: (1) integrating minimal residual disease into clinical trial design and practice; (2) the molecular and immunobiology of disease evolution and progression in myeloma; (3) adaptation of next-generation sequencing, next-generation flow cytometry, and cytometry by time of flight techniques; and (4) chimeric antigen receptor T-cell and other cellular therapies for myeloma. In this report, we provide a summary of the workshop presentations and discuss future directions in the field. |
| Databáze: | OpenAIRE |
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