Clinical–morphological profiles of esophageal carcinoma’s main types
| Autor: | Alin Demetrian, Iancu Emil Pleşea, Augustin Marian Marincaş, Elena Ioniţă, Dan Cameniţă, Manuela Ioana Tănasie-Vasile, Valentin Titus Grigorean, Victor Dan Eugen Strâmbu, Răzvan Mihail Pleşea |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Embryology Pathology medicine.medical_specialty Adolescent Esophageal Neoplasms Biology Pathology and Forensic Medicine Lesion Young Adult 03 medical and health sciences 0302 clinical medicine medicine Carcinoma Humans Esophagus Stage (cooking) Child Rest (music) Aged Poorly differentiated Infant Newborn Infant Cell Biology General Medicine Middle Aged medicine.disease Stenosis medicine.anatomical_structure Child Preschool 030220 oncology & carcinogenesis Lateral extension Female 030211 gastroenterology & hepatology medicine.symptom Developmental Biology |
| Zdroj: | Romanian Journal of Morphology and Embryology. 61:407-422 |
| ISSN: | 2066-8279 1220-0522 |
| Popis: | Aim The purpose of the study was to define and then to compare particularly the morphological profiles of the main morphological types of esophageal carcinoma (EC). Patients, materials and methods The studied group included 46 operated EC patients. Few parameters were clinical (gender and age). The rest of them described both gross and histological features of the entire group and of the two main histological types of carcinoma (lesion' site, lateral extension, lesion dimensions, gross aspect, and histological type, and tumor grade, and stage). Stratification scales of cases were defined according to each parameter in order to compare the data and a statistical apparatus [Student's t-test and χ² (chi-squared) test] was used. Results The studied tumors were encountered mostly in mature adult and elderly men, usually in the lower segments of the esophagus. Many of them had between five and ten cm in the long diameter and produced stenosis. Most of them had infiltrating appearance combined often with protruding or∕and ulcerated aspects. Usually, the tumors were poorly differentiated and in stage III. The two main histological types of EC showed different morphological profiles. Data from the literature revealed sometimes wide ranges of variation for the studied morphological parameters. Our results were within these ranges of variation. Conclusions ECs proved to be aggressive and late diagnosed tumors in general, with distinct morphological and behavioral profiles for the two main histological types. Comparisons with literature data confirmed many of our observations regarding the clinical and morphological aspects of both ECs as a whole and its histological types. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|