Mutagenicity of smoke condensates induced by CO2-laser irradiation and electrocauterization

Autor:	Tomita Yoshifumi, Ueda Setsuo, Nagata Kazuto, Hirano Minoru, Mihashi Shigenobu, Fujiki Masakazu, Hirohata Tomio
Rok vydání:	1981
Předmět:	Salmonella typhimurium Smoke endocrine system Co2 laser Chromatography Mutagenicity Tests Chemistry Lasers Revertant food and beverages Toxicology Rats Surgical smoke Mutagenic potency Electrocoagulation Microsomes Liver Genetics Animals Irradiation Electrocauterization Biotransformation Mutagens
Zdroj:	Mutation Research/Genetic Toxicology. 89:145-149
ISSN:	0165-1218
DOI:	10.1016/0165-1218(81)90120-8
Popis:	Smoke condensates generated from mucous membrane of the canine tongue irradiated with a CO2 laser showed mutagenicity on Salmonella typhimurium TA98 under metabolic activation with S9 mix. Strain TA100 was not so sensitive to the condensates with or without S9 mix. Smoke condensates from electrocauterization on the mucosa of the canine tongue also showed mutagenic activity on TA98 and TA100 with S9 mix. The revertant number per mg of the smoke condensates from laser irradiation was one-half that of the smoke condensates from electrocauterization (1623 and 3371) in TA98. The mutagenic potency observed was comparable to that of cigarette sn oke. The amount of these smoke condensates from 1 g of tissue was equivalent to those from 3–6 cigarettes as to total mutagenicity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78de3b25b36f138f7a0012f85fb57eb https://doi.org/10.1016/0165-1218(81)90120-8 Zobrazit plný text záznamu