Randomized Study of the Efficacy and Safety of Oral Elderberry Extract in the Treatment of Influenza A and B Virus Infections
| Autor: | E Thom, Z Zakay-Rones, J Wadstein, T Wollan |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Visual analogue scale Administration Oral Placebo Biochemistry Virus law.invention Placebos Randomized controlled trial Sambucus nigra law Internal medicine Influenza Human Humans Medicine Sinusitis Traditional medicine Plant Extracts business.industry Biochemistry (medical) Influenza a Cell Biology General Medicine medicine.disease Clinical trial Influenza B virus Treatment Outcome Tolerability Female business |
| Zdroj: | Journal of International Medical Research. 32:132-140 |
| ISSN: | 1473-2300 0300-0605 |
| DOI: | 10.1177/147323000403200205 |
| Popis: | Elderberry has been used in folk medicine for centuries to treat influenza, colds and sinusitis, and has been reported to have antiviral activity against influenza and herpes simplex. We investigated the efficacy and safety of oral elderberry syrup for treating influenza A and B infections. Sixty patients (aged 18-54 years) suffering from influenza-like symptoms for 48 h or less were enrolled in this randomized, double-blind, placebo-controlled study during the influenza season of 1999-2000 in Norway. Patients received 15 ml of elderberry or placebo syrup four times a day for 5 days, and recorded their symptoms using a visual analogue scale. Symptoms were relieved on average 4 days earlier and use of rescue medication was significantly less in those receiving elderberry extract compared with placebo. Elderberry extract seems to offer an efficient, safe and cost-effective treatment for influenza. These findings need to be confirmed in a larger study. |
| Databáze: | OpenAIRE |
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