Coenzyme A fuels T cell anti-tumor immunity

Autor: Michael St. Paul, Samuel D. Saibil, SeongJun Han, Kavita Israni-Winger, Scott C. Lien, Rob C. Laister, Azin Sayad, Susanne Penny, Rodabe N. Amaria, Lauren E. Haydu, Carlos R. Garcia-Batres, Meghan Kates, David T. Mulder, Céline Robert-Tissot, Matthew J. Gold, Charles W. Tran, Alisha R. Elford, Linh T. Nguyen, Trevor J. Pugh, Devanand M. Pinto, Jennifer A. Wargo, Pamela S. Ohashi
Rok vydání: 2021
Předmět:
Zdroj: Cell Metabolism. 33:2415-2427.e6
ISSN: 1550-4131
DOI: 10.1016/j.cmet.2021.11.010
Popis: Metabolic programming is intricately linked to the anti-tumor properties of T cells. To study the metabolic pathways associated with increased anti-tumor T cell function, we utilized a metabolomics approach to characterize three different CD8
Databáze: OpenAIRE