Nerve conduction velocity in the dog during hypothermia: effects of controlled hypercapnia

Autor: Kunio Ichiyanagi, Dochil Lee, Lucien E. Morris
Rok vydání: 1973
Předmět:
Zdroj: Canadian Anaesthetists' Society journal. 20(4)
ISSN: 0008-2856
Popis: Effects of hypothermia on the nerve conduction velocity and conduction time across the neuromuscular junction (terminal conduction time) were studied in the range between 35 and 23° C using thein situ ulnar nerve of the dog. Nerve conduction velocity decreased in linear fashion with the reduction in the perineural temperature at an average rate of 1.82 m/sec/°C. Recovery occurred in a similar linear relationship on rewarming but at the slightly lesser rate of 1.65 m/sec/°C. This rate of change in the conduction velocity was not altered by deliberate lowering of arterial blood pH according to a precalculated scale, i.e. 0.0147 pH unit decrease per degree centigrade fall of oesophageal temperature. These changes of pH were achieved by raising the PaCO2. The lack of effect of altered pH and PaCO2 is ascribed to the much greater effect of cold itself as compared to other environmental factors.
Databáze: OpenAIRE