Sweet liking in patients with Parkinson's disease
| Autor: | Wanda Lipczynska-Lojkowska, Wlodzimierz Kuran, Przemyslaw Bienkowski, Jerzy Samochowiec, Lukasz Swiecicki, Marcin Kołaczkowski, Danuta Ryglewicz, Halina Sienkiewicz-Jarosz, Anna Scinska |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Male
Olfactory system Sucrose Taste medicine.medical_specialty Levodopa Parkinson's disease Sensory system Olfaction Audiology Developmental psychology Antiparkinson Agents Food Preferences medicine Humans Taste Threshold Aged Analysis of Variance Dose-Response Relationship Drug Parkinson Disease Middle Aged medicine.disease Smell Neurology Sweetening Agents Female Neurology (clinical) Analysis of variance Psychology psychological phenomena and processes medicine.drug |
| Popis: | Pleasant tastes and odors are considered phylogenetically old natural rewards and their hedonic evaluation is regarded as a good indicator of the reward system function. The primary aim of the present study was to compare pleasantness ratings of sucrose solutions (1-30%, w/w) and sweet liking/disliking status in 20 patients with Parkinson's disease (PD) and in 20 age-matched healthy controls. In addition, basic sensory aspects of gustatory (intensity ratings, electrogustometric thresholds) and olfactory function (identification abilities in the Sniffin' Stick test) were assessed in both groups. The number of odors rated as pleasant, unpleasant, and neutral was also compared. As expected, the PD patients showed a significant impairment in olfactory identification abilities. There were no differences between the PD patients and controls in electrogustometric thresholds. Rated intensity of higher sucrose concentrations did not differ between the groups. The PD patients tended to rate water taste as more intense in comparison with the controls. Pleasantness ratings of sucrose solutions, the proportion of subjects rating 30% sucrose as the most pleasant (sweet likers), and the number of odors rated as pleasant did not differ between the study groups. The present results suggest that PD does not lead to any obvious alterations in pleasantness ratings of chemosensory stimuli. The study requires replication in larger samples. |
| Databáze: | OpenAIRE |
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