Antibacterial Activities of Transition Metal complexes of Mesocyclic Amidine 1,4-diazacycloheptane (DACH)
| Autor: | Muhammad Ikram, Waliullah Khan, Sadia Rehman, Fazle Subhan, Mutasem Omar Sinnokrot |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Chemistry
General Chemistry minimum inhibitory concentration 010402 general chemistry 01 natural sciences 0104 chemical sciences Amidine 1 4-diazacycloheptane Minimum inhibitory concentration chemistry.chemical_compound Transition metal bioassay Materials Chemistry Organic chemistry coordination complexes QD1-999 |
| Zdroj: | Open Chemistry, Vol 17, Iss 1, Pp 936-942 (2019) |
| ISSN: | 2391-5420 |
| Popis: | The titled compound 1,4-diazacycloheptane have vibrational freedom which allows it to coordinate to metal through 1st and 4th positions. Copper (II) and Nickel (II) complexes of DACH were prepared and characterized through UV-Visible, FT-IR, elemental analyses, conductance, and magnetic susceptibilities and compared to the results published in Inorg. Chem., 8(3), 528 (1969). The prepared complexes bearing different coordinating or non-coordinating anions were screened against four different pathogenic bacterial strains to study anionic effect on antibacterial activity. The MIC values of all the compounds suggest that [Cu(DACH)2Br2] is almost inactive against the tested microbes except Staph aureus. Rest of the metal complexes are active at their respective MIC values. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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