Influence of coronary artery diameter on eNOS protein content
Autor: | Elmer M. Price, James R. Turk, William G. Schrage, Christopher R. Woodman, M. H. Laughlin |
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Rok vydání: | 2003 |
Předmět: |
medicine.medical_specialty
Pathology Nitric Oxide Synthase Type III Endothelium Physiology Immunoblotting Hemodynamics Cell Count Muscle Smooth Vascular Veins Enos Physiology (medical) Internal medicine Animals Medicine biology business.industry biology.organism_classification Coronary Vessels Immunohistochemistry Capillaries Endothelial stem cell Coronary arteries Arterioles medicine.anatomical_structure Endocrinology Circulatory system Swine Miniature Female Endothelium Vascular Nitric Oxide Synthase Cardiology and Cardiovascular Medicine business Blood vessel Artery |
Zdroj: | American Journal of Physiology-Heart and Circulatory Physiology. 284:H1307-H1312 |
ISSN: | 1522-1539 0363-6135 |
DOI: | 10.1152/ajpheart.00792.2002 |
Popis: | The purpose of this study was to test the hypothesis that the content of endothelial nitric oxide synthase (eNOS) protein (eNOS protein/g total artery protein) increases with decreasing artery diameter in the coronary arterial tree. Content of eNOS protein was determined in porcine coronary arteries with immunoblot analysis. Arteries were isolated in six size categories from each heart: large arteries [301- to 2,500-microm internal diameter (ID)], small arteries (201- to 300-microm ID), resistance arteries (151- to 200-microm ID), large arterioles (101- to 150-microm ID), intermediate arterioles (51- to 100-microm ID), and small arterioles( |
Databáze: | OpenAIRE |
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