Influence of coronary artery diameter on eNOS protein content

Autor: Elmer M. Price, James R. Turk, William G. Schrage, Christopher R. Woodman, M. H. Laughlin
Rok vydání: 2003
Předmět:
Zdroj: American Journal of Physiology-Heart and Circulatory Physiology. 284:H1307-H1312
ISSN: 1522-1539
0363-6135
DOI: 10.1152/ajpheart.00792.2002
Popis: The purpose of this study was to test the hypothesis that the content of endothelial nitric oxide synthase (eNOS) protein (eNOS protein/g total artery protein) increases with decreasing artery diameter in the coronary arterial tree. Content of eNOS protein was determined in porcine coronary arteries with immunoblot analysis. Arteries were isolated in six size categories from each heart: large arteries [301- to 2,500-microm internal diameter (ID)], small arteries (201- to 300-microm ID), resistance arteries (151- to 200-microm ID), large arterioles (101- to 150-microm ID), intermediate arterioles (51- to 100-microm ID), and small arterioles(
Databáze: OpenAIRE