Benign Reactive Lymphoid Hyperplasia of the Conjunctiva Treated With Cyclosporine
| Autor: | Rupin N. Parikh, Scott M. Goldstein, Harpal Sandhu, Joan M OʼBrien, Giacomina Massaro-Giordano |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Conjunctiva genetic structures Treatment outcome medicine.disease_cause Conjunctival Diseases Lymphoid hyperplasia 03 medical and health sciences 0302 clinical medicine Pseudolymphoma medicine Humans Cyclosporine therapy Aged business.industry Meibomian gland dysfunction Matrix metalloproteinase 9 Dermatology eye diseases Ophthalmology Treatment Outcome medicine.anatomical_structure Cyclosporine 030221 ophthalmology & optometry sense organs medicine.symptom Irritation business Immunosuppressive Agents 030217 neurology & neurosurgery |
| Zdroj: | Cornea. 37:255-257 |
| ISSN: | 0277-3740 |
| DOI: | 10.1097/ico.0000000000001452 |
| Popis: | Purpose To describe a case of reactive lymphoid hyperplasia (RLH) of the conjunctiva responding to cyclosporine immunosuppressant monotherapy. Methods A 66-year-old man with a 2-year history of biopsy-proven bilateral RLH presented for dry eye evaluation with chief complaints of burning, stinging, and irritation in both eyes. After slit-lamp examination and positive findings of matrix metalloproteinase 9 in the patient's tear film, he was diagnosed with meibomian gland dysfunction and tear-insufficiency dry eye disease. The patient was subsequently treated with topical cyclosporine (ophthalmic emulsion 0.5 mg/mL two times per day) in both eyes. Results Examination at the 3-month follow-up visit revealed significant reduction of the RLH lesions bilaterally. Conclusions This report represents the first case of benign ocular RLH responsive to topical cyclosporine therapy. We believe that cyclosporine could play a role in treating patients with benign ocular RLH and warrants further investigation to evaluate its full efficacy. |
| Databáze: | OpenAIRE |
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