Radioimmunoassay and Some Properties of Human Antibodies to Hepatitis B Core Antigen
| Autor: | W. Szmuness, A. R. Neurath, E. J. Harley, N. Strick, C. E. Stevens |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Hepatitis
Hepatitis B virus viruses Radioimmunoassay virus diseases Biology Hepatitis B Antibodies Viral medicine.disease medicine.disease_cause Hepatitis B Core Antigens Virology digestive system diseases Pathogenesis Immune system Antigen Immunology medicine biology.protein Humans Hepatitis B Antibodies Antibody |
| Zdroj: | Journal of General Virology. 38:549-559 |
| ISSN: | 1465-2099 0022-1317 |
| DOI: | 10.1099/0022-1317-38-3-549 |
| Popis: | A solid-phase radioimmunoassay for antibodies to hepatitis B core antigen (anti-HBc) is described. Polystyrene beads coated with anti-HBc, hepatitis B core antigen prepared from pooled sera of humans infected with hepatitis B virus (HBV) and 125I-labelled anti-HBc were used for the test. Distinct patterns of development and changes of anti-HBc and their immunologic properties are all related to variations of other markers specific for HBV infections. Knowledge concerning the detailed features of the immune response to hepatitis B core antigen may provide deeper insight into the pathogenesis of HBV infections. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|