Ventilation and Haemodynamic Indicators in Spontaneously Breathing Pigs under General Anaesthesia
| Autor: | Vladislav Třeška, J Fremuth, J Kobr, Václav Vobruba, Jiří Moláček, Vilém Kuntscher |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Cardiac output
model lcsh:Veterinary medicine General Veterinary business.industry medicine.medical_treatment Pulmonary artery catheter Pulmonary compliance piglets medicine.anatomical_structure Afterload Anesthesia medicine Vascular resistance Breathing lcsh:SF600-1100 General anaesthesia general anaesthesia business Tidal volume |
| Zdroj: | Acta Veterinaria Brno, Vol 79, Iss 1, Pp 61-65 (2010) |
| ISSN: | 1801-7576 0001-7213 |
| Popis: | The aim of this study was to obtain ventilation and haemodynamic data of healthy piglets under general anaesthesia for future patho-physiological experimental studies. A total of 34 domestic piglets of the Czech Black Pied (Přeštice) breed were used in the study. The animals (male to female ratio 8 : 9) were six weeks old and their average body mass was 22 kg. A general anaesthetic (fentanyl and azaperon) was introduced via a pulmonary artery catheter and the spontaneously breathing animals were monitored for 60 min. Cardiac output and haemodynamic indicators were established using intermittent pulmonary artery thermodilution. Blood gas data were deduced using fan dynamic parameters of ventilation and ventilation indices. The study yielded reliable data of dynamic lung indicators (p < 0.05); e.g. the tidal volume 6.00 ± 0.82 ml/kg, hypoxemic index 350.47 ± 42.50 mmHg, lung compliance 0.63 ± 0.12 ml/cmH2O/kg, and haemodynamic indicators (p < 0.01) such as cardiac output 2.12 ± 0.75 l/min, pulmonary vascular resistance 3.92 ± 0.52 and systemic vascular resistance 15.8 ± 6.81 Woods units. Reliable data regarding lung dynamics, cardiac output, preload and afterload of both heart ventricles in spontaneously breathing healthy piglets under general anaesthesia were achieved. |
| Databáze: | OpenAIRE |
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