Cholesteatoma and meningoencephalitis in a dog with chronic otitis externa
| Autor: | Meegan Larsen, Chelsie M. Estey, Sofia Cerda-Gonzalez, Ashleigh W. Newman, Tracy Stokol, Sean P. McDonough |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty Ear infection Ear Middle Dogs Meningoencephalitis Biopsy otorhinolaryngologic diseases medicine Animals Dog Diseases Postoperative Period Cholesteatoma Pleocytosis General Veterinary medicine.diagnostic_test business.industry Anatomy Epidermoid cyst Otitis Externa medicine.disease Magnetic Resonance Imaging Osteotomy medicine.anatomical_structure Chronic Disease Middle ear Female business Bulla (amulet) Ear Canal |
| Zdroj: | Veterinary Clinical Pathology. 44:157-163 |
| ISSN: | 0275-6382 |
| DOI: | 10.1111/vcp.12212 |
| Popis: | A 10-year-old female spayed German Shepherd dog, with a year-long history of recurrent left ear infections, was presented for progressive ataxia, head tilt, and pain on opening of the mouth. On physical examination, a large amount of ceruminous debris was present in the left ear and multiple neurologic defects localizing to the cerebellum and vestibular system were identified. Magnetic resonance imaging (MRI) demonstrated a minimally contrast-enhancing mass within the left bulla, an intracranial space-occupying, heterogeneously contrast-enhancing lesion at the level of the left cerebello-medullary junction, and contrast enhancement of the ipsilateral meninges. Cerebrospinal fluid analysis revealed a marked mixed cell pleocytosis (nucleated cell count 655 cells/μL). The mass was visualized within the horizontal ear canal by otoscopic examination and a biopsy was taken. Impression smears of the biopsy contained many anucleate keratinized squamous epithelial cells, mild mixed inflammation, and few presumptive fibroblasts. With the provided clinical history and MRI findings, a cytologic diagnosis of cholesteatoma was made. A ventral bulla osteotomy was performed, and histopathologic examination of resected tissue confirmed the cytologic diagnosis of cholesteatoma. The dog's clinical symptoms improved postoperatively, but the dog died of unrelated causes, 3.5 months later. To our knowledge, this is the first description of the cytologic features of a cholesteatoma, which is a nonneoplastic, but locally invasive epidermoid cyst, in the middle ear of dogs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text