Altered laboratory thyroid parameters indicating hypothyroidism in elderly subjects
| Autor: | M. S. Russo, Giuseppe Romano, Salvatore Catanzaro, Massimo Motta, Fabio Di Stefano, Carmela Franze, Piera Panebianco, G. Carnazzo, Domenico Maugeri, Sabrina Campagna |
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| Rok vydání: | 1996 |
| Předmět: |
endocrine system
Aging medicine.medical_specialty Health (social science) endocrine system diseases business.industry Thyroid Physiology medicine.anatomical_structure Endocrinology Internal medicine medicine Geriatrics and Gerontology business Gerontology hormones hormone substitutes and hormone antagonists |
| Zdroj: | Archives of Gerontology and Geriatrics. 23:61-70 |
| ISSN: | 0167-4943 |
| Popis: | The altered laboratory thyroid parameters indicating hypothyroidism were evaluated in a series of 3015 subjects over 65 years of age by determining total T3, total T4 and TSH. In addition, clinical signs of hypothyroidism were recorded in a subsample of 300 randomly selected elderly. Our results showed a high prevalence of altered laboratory thyroid parameters indicating hypothyroidism of 17.88%, whereas the real prevalence (both clinical and laboratory) is 1.00% with a female/male ratio of 2.00. The most frequent laboratory alterations was the so-called 'alerted pituitary' status'. The most common clinical signs of hypothyroidism involved the nervous system. We conclude that it is very difficult to diagnose hypothyroidism in the elderly and that the most indicative laboratory alterations seem to be TSH values above 3 IU/ml determined using the IRMA method. |
| Databáze: | OpenAIRE |
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