What increases the risk of malnutrition in Parkinson's disease?
| Autor: | Svetlana Tomić, Zeljka Popijac, Ruzica Palic Kramaric, Sanja Mišević, Tomislav Pucic, Marta Petek, Tihana Gilman Kuric, Vlasta Pekić |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine Pediatrics medicine.medical_specialty Parkinson's disease Statistics as Topic Disease Severity of Illness Index Body Mass Index 03 medical and health sciences Sex Factors 0302 clinical medicine Rating scale medicine Humans Aged Aged 80 and over Psychiatric Status Rating Scales Malnutrition Nutritional assessment Parkinson disease Risk factors 030109 nutrition & dietetics Mini–Mental State Examination Pramipexole medicine.diagnostic_test business.industry Age Factors Beck Depression Inventory Parkinson Disease Middle Aged medicine.disease Cross-Sectional Studies Ropinirole Neurology Physical therapy Female Neurology (clinical) business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Journal of the Neurological Sciences. 375:235-238 |
| ISSN: | 0022-510X |
| Popis: | Parkinson's disease (PD) patients are at a higher risk of malnutrition. The prevalence has been estimated to 0–24%, while 3%–60% of PD patients are reported to be at risk of malnutrition. To date, there is no clear explanation for malnutrition in these patients. The aim of this study was to determine the prevalence of malnutrition and to analyze factors that influence its appearance. The Mini Nutritional Assessment (MNA) was used to determine normal nutritional status ; at risk of malnutrition ; and already malnourished status. The Unified Parkinson's Disease Rating Scale (UPDRS) parts III and IV, Hoehn and Yahr scale (H&Y scale), Beck Depression Inventory (BDI), Mini Mental State Examination (MMSE), Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease-Rating Scale - eating part (QUIP-RS) and Mini Nutritional Assessment (MNA) were used to evaluate the factors affecting patient nutritional status. Out of 96 patients, 55, 2% were at risk of malnutrition, while 8, 3% had already been malnourished. Age, H&Y scale, UPDRS part III, ‘off’ periods and depression influence negatively on MNA. More patients with ‘off’ periods were rigor dominant. Thyroid gland hormone therapy was related to malnutrition, while patients with normal nutritional status used ropinirole more often than pramipexole. Factors affecting nutritional status are age, motor symptoms and stage severity, ‘off’ states, rigidity dominant type with ‘off’ states, and thyroid hormone replacement therapy. Ropinirole exhibited the possible ‘protective’ effect against malnutrition. |
| Databáze: | OpenAIRE |
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