The value of magnetic resonance spectroscopy as a supplement to MRI of the brain in a clinical setting
| Autor: | Raili Raininko, Sylwia Libard, Jussi Hellström, Johan Wikström, Irina Alafuzoff, Romina Romanos Zapata, Francisco Ortiz-Nieto |
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| Rok vydání: | 2017 |
| Předmět: |
In vivo magnetic resonance spectroscopy
Male Magnetic Resonance Spectroscopy lcsh:Medicine Pathology and Laboratory Medicine 030218 nuclear medicine & medical imaging Diagnostic Radiology Metastasis 0302 clinical medicine Basic Cancer Research Medicine and Health Sciences Medicine Medical diagnosis lcsh:Science Child Neurological Tumors Aged 80 and over Multidisciplinary medicine.diagnostic_test Clinical Laboratory Medicine Brain Neoplasms Radiology and Imaging Brain Glioma Middle Aged Magnetic Resonance Imaging Klinisk laboratoriemedicin Oncology Neurology Child Preschool Female Radiology Chemical shift imaging Radiology Nuclear Medicine and Medical Imaging Research Article Adult medicine.medical_specialty Adolescent Imaging Techniques Research and Analysis Methods 03 medical and health sciences Signs and Symptoms Diagnostic Medicine Cancer Detection and Diagnosis Humans Aged Retrospective Studies business.industry lcsh:R Infant Newborn Infant Cancers and Neoplasms Magnetic resonance imaging Single voxel spectroscopy Clinical value Lesions lcsh:Q Radiologi och bildbehandling business 030217 neurology & neurosurgery |
| Zdroj: | PLoS ONE PLoS ONE, Vol 13, Iss 11, p e0207336 (2018) |
| ISSN: | 1932-6203 |
| Popis: | Background There are different opinions of the clinical value of MRS of the brain. In selected materials MRS has demonstrated good results for characterisation of both neoplastic and non-neoplastic lesions. The aim of this study was to evaluate the supplemental value of MR spectroscopy (MRS) in a clinical setting. Material and methods MRI and MRS were re-evaluated in 208 cases with a clinically indicated MRS (cases with uncertain or insufficient information on MRI) and a confirmed diagnosis. Both single voxel spectroscopy (SVS) and chemical shift imaging (CSI) were performed in 105 cases, only SVS or CSI in 54 and 49 cases, respectively. Diagnoses were grouped into categories: non-neoplastic disease, low-grade tumour, and high-grade tumour. The clinical value of MRS was considered very beneficial if it provided the correct category or location when MRI did not, beneficial if it ruled out suspected diseases or was more specific than MRI, inconsequential if it provided the same level of information, or misleading if it provided less or incorrect information. Results There were 70 non-neoplastic lesions, 43 low-grade tumours, and 95 high-grade tumours. For MRI, the category was correct in 130 cases (62%), indeterminate in 39 cases (19%), and incorrect in 39 cases (19%). Supplemented with MRS, 134 cases (64%) were correct, 23 cases (11%) indeterminate, and 51 (25%) incorrect. Additional information from MRS was beneficial or very beneficial in 31 cases (15%) and misleading in 36 cases (17%). Conclusion In most cases MRS did not add to the diagnostic value of MRI. In selected cases, MRS may be a valuable supplement to MRI. |
| Databáze: | OpenAIRE |
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